Impact of virus aggregation on disinfection

摘要: This study is based on the hypothesis that viral aggregation slows inactivation by chemical disinfectants. slow-down depends aggregate size, concentration and reactivity of disinfectant. In this work we test experimentally investigating MS2 coliphage aggregates dichloramine PhiX174 PAA. The experiments performed with show good adherence to theory. We observed was slowed 3.4 13 times size between 420 580 nm, a varying 3.5 mg/L. larger aggregates, higher disinfection, greater inhibition due aggregates. Comparing PAA, stronger disinfectant, impact dichlormaine more extensive. permitted verify reactive disinfectant sensitive aggregation. Our results were furthermore in agreement mechanistic model for developed Mattle et al. (2011). contrast MS2, disinfection did not exhibit an effect disinfection. hypothesize viruses within sufficiently compact result phenomenon probably spikes capsid. Structural features thus influence their propensity inhibit inactivation.