A daily vasopressin rhythm in rat cerebrospinal fluid.
作者： William J. Schwartz , Robert J. Coleman , Steven M. Reppert
DOI: 10.1016/0006-8993(83)91205-2
关键词:
摘要: Cerebrospinal fluid (CSF) was serially withdrawn in individual, unanesthetized, unrestrained rats and assayed for vasopressin using a sensitive specific radioimmunoassay. A prominent daily rhythm the CSF concentrations of this peptide found under diurnal lighting conditions. Low levels during dark period alternated with high values light period; appeared to anticipate artificial 'dawn' 'dusk' by few hours. An 8-h phase shift caused corresponding rhythm. In addition, persisted at least 10 days absence periodic environmental cues animals blinded bilateral orbital enucleation; disrupted after constant light. Blood did not show Our results indicate that rodent is endogenously generated its synchronized light-dark cycle.
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sci-hub.se 参考文章(43)
Benjamin Rusak, Vertebrate Behavioral Rhythms Biological Rhythms. pp. 183- 213 ,(1981) , 10.1007/978-1-4615-6552-9_11
Thomas G. Luerssen, Gary L. Robertson, Cerebrospinal Fluid Vasopressin and Vasotocin in Health and Disease Neurobiology of Cerebrospinal Fluid 1. pp. 613- 623 ,(1980) , 10.1007/978-1-4684-1039-6_43
Gary M. Peterson, Watkins Wayne B., Robert Y. Moore, The suprachiasmatic hypothalamic nuclei of the rat. VI. Vasopressin neurons and circadian rhythmicity. Behavioral and Neural Biology. ,vol. 29, pp. 236- 245 ,(1980) , 10.1016/S0163-1047(80)90573-7
David Rodbard, Statistical Quality Control and Routine Data Processing for Radioimmunoassays and Immunoradiometric Assays Clinical Chemistry. ,vol. 20, pp. 1255- 1270 ,(1974) , 10.1093/CLINCHEM/20.10.1255
Janet Hawthorn, Vincent T.Y. Ang, John S. Jenkins, Localization of vasopressin in the rat brain. Brain Research. ,vol. 197, pp. 75- 81 ,(1980) , 10.1016/0006-8993(80)90435-7
R. M. Buijs, D. F. Swaab, J. Dogterom, F. W. van Leeuwen, Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat Cell and Tissue Research. ,vol. 186, pp. 423- 433 ,(1978) , 10.1007/BF00224932
Mitchell L. Berk, Judith A. Finkelstein, An autoradiographic determination of the efferent projections of the suprachiasmatic nucleus of the hypothalamus Brain Research. ,vol. 226, pp. 1- 13 ,(1981) , 10.1016/0006-8993(81)91079-9
N. W. Kasting, W. L. Veale, K. E. Cooper, Convulsive and hypothermic effects of vasopressin in the brain of the rat. Canadian Journal of Physiology and Pharmacology. ,vol. 58, pp. 316- 319 ,(1980) , 10.1139/Y80-054
B Rusak, G Groos, Suprachiasmatic stimulation phase shifts rodent circadian rhythms Science. ,vol. 215, pp. 1407- 1409 ,(1982) , 10.1126/SCIENCE.7063851
W. Tapp, F. Holloway, Phase Shifting Circadian Rhythms Produces Retrograde Amnesia Science. ,vol. 211, pp. 1056- 1058 ,(1981) , 10.1126/SCIENCE.7193351