Effects of Zn-Doped Mesoporous Bioactive Glass Nanoparticles in Etch-and-Rinse Adhesive on the Microtensile Bond Strength.
作者： Yeonju Choi , Woogyeong Sun , Yeon Kim , In-Ryoung Kim , Mi-Kyung Gong
DOI: 10.3390/NANO10101943
关键词:
摘要: The purpose of this study was to assess the effects in dentin bond strength dental adhesives (DAs) and biological using zinc (Zn)-doped mesoporous bioactive glass nanoparticles (MBN-Zn). Synthesized MBN MBN-Zn were characterized by scanning electron microscopy (SEM), X-ray diffraction Brunauer, Emmett Teller (BET) method. matrix metalloproteinases (MMP) inhibition DA-MBN DA-MBN-Zn analyzed. microtensile (MTBS) test conducted before after thermocycling investigate on MTBS DAs. properties analyzed with human pulp stem cells (hDPSCs). Compared DA, only DA-1.0% exhibited a statistically significant decrease MMP activity. values significantly increased compared DA (p < 0.05). It confirmed via MTT assay that there no cytotoxicity for hDPSCs at 50% extract. In addition, increases alkaline phosphatase activity Alizarin Red S staining observed DA-1.0%MBN-Zn. These data suggest 1.0% enhance remineralization capability DAs stabilize long-term inhibiting MMPs.
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scilit.net参考文章(59)
David H. Pashley, Franklin Chi Meng Tay, Dental adhesives of the future. Journal of Adhesive Dentistry. ,vol. 4, pp. 91- 103 ,(2002)
Constance E. Brinckerhoff, Lynn M. Matrisian, Matrix metalloproteinases: a tail of a frog that became a prince Nature Reviews Molecular Cell Biology. ,vol. 3, pp. 207- 214 ,(2002) , 10.1038/NRM763
Raquel Osorio, Mónica Yamauti, Estrella Osorio, María E. Ruiz-Requena, David Pashley, Franklin Tay, Manuel Toledano, Effect of dentin etching and chlorhexidine application on metalloproteinase-mediated collagen degradation. European Journal of Oral Sciences. ,vol. 119, pp. 79- 85 ,(2011) , 10.1111/J.1600-0722.2010.00789.X
Jorge Perdigão, Alessandra Reis, Alessandro D. Loguercio, Dentin Adhesion and MMPs: A Comprehensive Review Journal of Esthetic and Restorative Dentistry. ,vol. 25, pp. 219- 241 ,(2013) , 10.1111/JERD.12016
Virgílio Vilas Boas Fernandes Jr, José Roberto Rodrigues, João Maurício Ferraz da Silva, Clóvis Pagani, Henderson Malaquias, Ivan Balducci, Microtensile bond strength of two self-adhesive cements to enamel and dentin: bonding efficiency and thermocycling effect Brazilian dental science. ,vol. 15, pp. 33- 38 ,(2012) , 10.14295/BDS.2012.V15I1.713
Merja Sulkala, Taina Tervahartiala, Timo Sorsa, Markku Larmas, Tuula Salo, Leo Tjäderhane, Matrix metalloproteinase-8 (MMP-8) is the major collagenase in human dentin Archives of Oral Biology. ,vol. 52, pp. 121- 127 ,(2007) , 10.1016/J.ARCHORALBIO.2006.08.009
M Hashimoto, H Ohno, M Kaga, H Sano, F.R Tay, H Oguchi, Y Araki, M Kubota, Over-etching effects on micro-tensile bond strength and failure patterns for two dentin bonding systems. Journal of Dentistry. ,vol. 30, pp. 99- 105 ,(2002) , 10.1016/S0300-5712(02)00004-0
Manuel Toledano, Monica Yamauti, María Estrella Ruiz-Requena, Raquel Osorio, A ZnO-doped adhesive reduced collagen degradation favouring dentine remineralization Journal of Dentistry. ,vol. 40, pp. 756- 765 ,(2012) , 10.1016/J.JDENT.2012.05.007
Jongryul Kim, Toshikazu Uchiyama, Marcela Carrilho, Kelli A. Agee, Annalisa Mazzoni, Lorenzo Breschi, Ricardo M. Carvalho, Leo Tjäderhane, Stephen Looney, Courtney Wimmer, Arzu Tezvergil-Mutluay, Franklin R. Tay, David H. Pashley, Chlorhexidine binding to mineralized versus demineralized dentin powder Dental Materials. ,vol. 26, pp. 771- 778 ,(2010) , 10.1016/J.DENTAL.2010.04.001
C. Xie, Y. Han, X. Y. Zhao, Z. Y. Wang, H. M. He, Microtensile bond strength of one- and two-step self-etching adhesives on sclerotic dentin: the effects of thermocycling. Operative Dentistry. ,vol. 35, pp. 547- 555 ,(2010) , 10.2341/10-025-L