t(3;9;22) 3-way chromosome translocation in chronic myeloid leukemia is associated with poor prognosis.
作者： Jiahuai Tan , Shundong Cang , Karen Seiter , Suneeta Primanneni , Nasir Ahmed
DOI: 10.1080/07357900802653498
关键词:
摘要: Chronic myelogenous leukemia (CML) is genetically characterized by the reciprocal translocation of chromosome 9 and 22. Around 5-8% CML develop complex variant Ph translocations involving one or more chromosomal regions besides Chromosome 3 not frequently involved in CML. We report this study a case displaying t(3;9;22) 3-way translocation. A review literature appears to indicate that patients with tend have an aggressive course poor outcome. Additional associated are also reviewed.
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