Liver ischemic preconditioning: a new strategy for the prevention of ischemia-reperfusion injury.
作者： C Peralta , A Serafin , L Fernández-Zabalegui , Z.Y Wu , J Roselló-Catafau
DOI: 10.1016/S0041-1345(03)00571-2
关键词:
摘要: Ischemic preconditioning renders the liver more tolerant to ischemia-reperfusion injury in warm and cold models. In general, application of a 5 10-minute period ischemia followed by 10 minutes reperfusion confers early effective protection liver. Mechanisms responsible for this endogenous protective effect include: (1) transient nitric oxide production during preconditioning; (2) diminution toxic reactive species generated on reperfusion; (3) remote extrahepatic organs such as lung, kidney, pancreas; (4) preservation energy metabolism ischemia; (5) involvement nuclear transcription factor others.
elsevier.com
sci-hub.se 参考文章(27)
D. Winlaw, M. Hicks, P. Macdonald, Zu Ying Du, P. Spratt, Ischemic preconditioning enhances donor lung preservation in the rat Journal of Heart and Lung Transplantation. ,vol. 15, pp. 1258- 1267 ,(1996)
Rocco Ricciardi, Shimul A Shah, Suzanne M Wheeler, Steven H Quarfordt, Mark P Callery, William C Meyers, Ravi S Chari, Regulation of NFκB in hepatic ischemic preconditioning1 Journal of The American College of Surgeons. ,vol. 195, pp. 319- 326 ,(2002) , 10.1016/S1072-7515(02)01229-2
C Peralta, Preconditioning protects against systemic disorders associated with hepatic ischemia-reperfusion through blockade of tumor necrosis factor-induced P-selectin up-regulation in the rat. Hepatology. ,vol. 33, pp. 100- 113 ,(2001) , 10.1053/JHEP.2001.20529
C. Peralta, D. Closa, G. Hotter, E. Gelpı́, N. Prats, J. Roselló-Catafau, Liver Ischemic Preconditioning Is Mediated by the Inhibitory Action of Nitric Oxide on Endothelin Biochemical and Biophysical Research Communications. ,vol. 229, pp. 264- 270 ,(1996) , 10.1006/BBRC.1996.1790
C. Y Pang, R. Z Yang, A. Zhong, N. Xu, B. Boyd, C. R Forrest, Acute ischaemic preconditioning protects against skeletal muscle infarction in the pig Cardiovascular Research. ,vol. 29, pp. 782- 788 ,(1995) , 10.1016/S0008-6363(96)88613-5
C Peralta, Adenosine monophosphate-activated protein kinase mediates the protective effects of ischemic preconditioning on hepatic ischemia-reperfusion injury in the rat. Hepatology. ,vol. 34, pp. 1164- 1173 ,(2001) , 10.1053/JHEP.2001.29197
Carmen Peralta, Georgina Hotter, Daniel Closa, Neus Prats, Carme Xaus, Emilio Gelpí, Joan Roselló-Catafau, The protective role of adenosine in inducing nitric oxide synthesis in rat liver ischemia preconditioning is mediated by activation of adenosine A2 receptors Hepatology. ,vol. 29, pp. 126- 132 ,(1999) , 10.1002/HEP.510290104
G. F. Baxter, P. Ferdinandy, Delayed preconditioning of myocardium: current perspectives Basic Research in Cardiology. ,vol. 96, pp. 329- 344 ,(2001) , 10.1007/S003950170041
Pierre-Alain Clavien, Surinder Yadav, David Sindram, Rex C Bentley, None, Protective effects of ischemic preconditioning for liver resection performed under inflow occlusion in humans. Annals of Surgery. ,vol. 232, pp. 155- 162 ,(2000) , 10.1097/00000658-200008000-00001
Leticia Fernández, Nicolás Heredia, Luis Grande, Gloria Gómez, Antonio Rimola, Alberto Marco, Emilio Gelpı́, Joan Roselló-Catafau, Carmen Peralta, Preconditioning protects liver and lung damage in rat liver transplantation: role of xanthine/xanthine oxidase. Hepatology. ,vol. 36, pp. 562- 572 ,(2002) , 10.1053/JHEP.2002.34616