Injection site reactions and antibody responses in sheep and goats after the use of multivalent clostridial vaccines

摘要: Uncertainty concerning the use, efficacy and possible adverse effects of clostridial vaccination in goats prompted a study injection site reactions antibody responses 40 sheep. The vaccines used were Covexin 8, Heptavac Tasvax 8. In all animals swellings averaging 2.5 cm diameter present at seven days after still apparent 28 vaccination. could not be attributed to faulty technique because they did occur control group injected with sterile water. By 14 significantly larger sheep than by 8 those other goats. Serum was groups before and, exception vaccinated Heptavac, increased increase greater levels had declined but which further occurred. At that time, higher unvaccinated whereas no longer different from These results suggest there is difference between two species support clinical observation protection afforded multivalent poorer