Assessing Antiviral Countermeasures Using Mouse Models of Ebolavirus Infection.

作者: Bryan D. Griffin , Xiangguo Qiu , Gary Kobinger , Andrea Kroeker

DOI: 10.1007/978-1-4939-7116-9_22

关键词:

摘要: Mouse models of Ebola virus (EBOV) have demonstrated their utility as important tools for screening the efficacy candidate therapeutics and vaccines. In this chapter we explain various mouse that utilize either wild-type or mouse-adapted EBOV variants.

参考文章(38)
Gary Wong, Xiangguo Qiu, Development of experimental and early investigational drugs for the treatment of Ebola virus infections Expert Opinion on Investigational Drugs. ,vol. 24, pp. 999- 1011 ,(2015) , 10.1517/13543784.2015.1052403
Amy C Shurtleff, Sina Bavari, Animal models for ebolavirus countermeasures discovery: what defines a useful model? Expert Opinion on Drug Discovery. ,vol. 10, pp. 685- 702 ,(2015) , 10.1517/17460441.2015.1035252
Janan T. Eppig, Howie Motenko, Joel E. Richardson, Beverly Richards-Smith, Cynthia L. Smith, The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources Mammalian Genome. ,vol. 26, pp. 448- 455 ,(2015) , 10.1007/S00335-015-9600-0
Jennifer M. Brannan, Jeffery W. Froude, Laura I. Prugar, Russell R. Bakken, Samantha E. Zak, Sharon P. Daye, Catherine E. Wilhelmsen, John M. Dye, Interferon α/β Receptor–Deficient Mice as a Model for Ebola Virus Disease The Journal of Infectious Diseases. ,vol. 212, ,(2015) , 10.1093/INFDIS/JIV215
Lorna Vanderzanden, Mike Bray, Deborah Fuller, Tim Roberts, David Custer, Kristin Spik, Peter Jahrling, John Huggins, Alan Schmaljohn, Connie Schmaljohn, DNA vaccines expressing either the GP or NP genes of Ebola virus protect mice from lethal challenge. Virology. ,vol. 246, pp. 134- 144 ,(1998) , 10.1006/VIRO.1998.9176
Lisa Oestereich, Anja Lüdtke, Stephanie Wurr, Toni Rieger, César Muñoz-Fontela, Stephan Günther, Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model Antiviral Research. ,vol. 105, pp. 17- 21 ,(2014) , 10.1016/J.ANTIVIRAL.2014.02.014
D. Bente, J. Gren, J. E. Strong, H. Feldmann, Disease modeling for Ebola and Marburg viruses Disease Models & Mechanisms. ,vol. 2, pp. 12- 17 ,(2009) , 10.1242/DMM.000471
A. L. Rasmussen, A. Okumura, M. T. Ferris, R. Green, F. Feldmann, S. M. Kelly, D. P. Scott, D. Safronetz, E. Haddock, R. LaCasse, M. J. Thomas, P. Sova, V. S. Carter, J. M. Weiss, D. R. Miller, G. D. Shaw, M. J. Korth, M. T. Heise, R. S. Baric, F. P.-M. de Villena, H. Feldmann, M. G. Katze, Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance Science. ,vol. 346, pp. 987- 991 ,(2014) , 10.1126/SCIENCE.1259595
Patrick Iversen, Travis Warren, Jay Wells, Nicole Garza, Dan Mourich, Lisa Welch, Rekha Panchal, Sina Bavari, Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections. Viruses. ,vol. 4, pp. 2806- 2830 ,(2012) , 10.3390/V4112806
Gary P. Kobinger, Heinz Feldmann, Yan Zhi, Gregory Schumer, Guangping Gao, Friederike Feldmann, Steven Jones, James M. Wilson, Chimpanzee adenovirus vaccine protects against Zaire Ebola virus. Virology. ,vol. 346, pp. 394- 401 ,(2006) , 10.1016/J.VIROL.2005.10.042