Blood Transfusion After Percutaneous Coronary Intervention and Risk of Subsequent Adverse Outcomes: A Systematic Review and Meta-Analysis.

摘要: Abstract Objectives This study sought to define the prevalence and prognostic impact of blood transfusions in contemporary percutaneous coronary intervention (PCI) practice. Background Although presence anemia is associated with adverse outcomes patients undergoing PCI, the optimal use products PCI remains controversial. Methods A search EMBASE MEDLINE was conducted identify studies that evaluated their association major cardiac events (MACE) mortality. Two independent reviewers screened for inclusion, data were extracted from relevant studies. Random effects meta-analysis used estimate risk transfusions. Statistical heterogeneity assessed by considering I2 statistic. Results Nineteen included 2,258,711 more than 54,000 transfusion identified (prevalence 2.3%). Crude mortality rate 6,435 50,979 (12.6%, 8 studies) who received a 27,061 2,266,111 (1.2%, remaining patients. MACE rates 17.4% (8,439 48,518) had 3.1% (68,062 2,212,730) cohort. Meta-analysis demonstrated independently an increase (odds ratio: 3.02, 95% confidence interval: 2.16 4.21, I2 = 91%) (odds ratio: 3.15, 2.59 3.82, 81%). Similar observations recorded adjusted baseline hematocrit, anemia, bleeding. Conclusions Blood increased events. Clinicians should minimize periprocedural using available bleeding-avoidance strategies and avoiding liberal practices.