Heart rate variability in horses with acute gastrointestinal disease requiring exploratory laparotomy.

摘要: Objective To describe heart rate variability (HRV) in horses with acute gastrointestinal disease that undergo exploratory laparotomy. We hypothesized ischemic will have reduced HRV compared to nonischemic lesions. further a reduction be associated nonsurvival. Design Prospective, clinical, observational study. Setting University veterinary teaching hospital. Animals Horses presented for colic (n = 57) or elective surgical procedures 10) were enrolled. Interventions Admission (HR) was recorded and within 2 hours of recovery from general anesthesia continuous telemetry placed, monitored 48-52 postoperatively. Stored electrocardiograms manually inspected R-to-R intervals extracted uploaded into software analysis. Time domain frequency spectral analysis investigated at Times 1 (2–10 h), (16–24 3 (30–38 4 (44–52 h) A two-way ANOVA repeated measures used group comparisons. Logistic regression detect potential associations between admission HR, time variables, nonsurvival. Measurements Main Results Horses diagnosed an lesion 22) the surgery had significantly higher postoperative rates domain-derived than lesions 35) control 10). Horses survived discharge lower HRs, domain, low nonsurvivors. The multivariable logistic model receiver operating characteristic area under curve (AUC) 0.95 better predicting nonsurvival HR (P 0.0124). Conclusions Reduced strongly nonsurvival. is noninvasive technique may provide diagnostic prognostic information pertinent management severe disease.