I. Immunosurveillance and tumorigenesis in BALB/c mice—1. Early reactive state in Peyer's patches

作者: V.A Toma , F.P Retief

DOI: 10.1016/0147-9571(79)90057-2

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摘要: Abstract Monthly i.p. injections of mineral oil in BALB/c mice will start to produce, after 6 months, plasma cell tumours (PCT). During the first month artificial induction PCT, animals mount an immune response injected antigens. The situ cellular Peyer's patches during tumour was studied. Original results: 1. (1) T-cellular response, this place using experimental model, is not achieved by multiplication. 2. (2) B-cellular showed following aberration if compared with physioloical [28]: B-B co-operation present because absence microvilli. Based on these findings, concept can now be enriched, it a dynamic, antigen and time-dependent phenomenon, may influenced serum factors which AgAb complexes enhance Ag 2 Ab suppress its course. role local limited recognition processing confirmed.

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