Interface corneal edema secondary to steroid-induced elevation of intraocular pressure simulating diffuse lamellar keratitis.

摘要: PURPOSE To describe interface corneal edema secondary to steroid-induced elevation of intraocular pressure (IOP) following LASIK. METHODS Retrospective observational case series. Diffuse IOP was observed after LASIK simulating diffuse lamellar keratitis (DLK) in 13 eyes. Mean patient age 31.4 +/- 5.3 years. Patients were divided into two groups according provisional misdiagnosis: DLK group (group 1) comprised 11 eyes and infection 2) 2 (microbial keratitis). follow-up 8.1 0.5 weeks. RESULTS In the group, typical haze confined extended visual axis, impairing vision all Provisional diagnosis late-onset topical steroids started. Repeat examination showed elevated as measured at center periphery using applanation tonometry (mean 19.1 mmHg 39.5 mmHg, respectively), causing with evident fluid pockets. Steroids stopped anti-glaucoma therapy The decreased end transparency restored dropped normal values. demonstrated a microbial keratitis-like reaction underwent flap lifting wound debridement biopsy administration fortified antibiotics steroids. After detected, started, resulting resolution edema. CONCLUSIONS Interface syndrome might develop steroid responders misleading clinical picture or infectious keratitis. Management includes stopping starting antiglaucoma therapy.