Long-distance feedback projections to area V1: Implications for multisensory integration, spatial awareness, and visual consciousness

摘要: It is generally agreed that information flow through the cortex constrained by a hierarchical architecture. Recent experimental evidence suggests projections descending hierarchy and targeting primary visual (area V1) may play an essential role in perceptual processes. We have, therefore, reexamined feedback to area V1, using retrograde tracer injections this area. In addition well-known areas, quantification of labeling higher cortical areas reveals number hitherto unknown long-distance connections originating from auditory (A1), multisensory (STP) cortices, but also perirhinal (36). These advanced stations, global feature shared belong ventral stream, could important early integration spatial awareness provide physical substrate for involvement V1 consciousness.