Role of Disulfide Bonds in Peptide and Protein Conformation
作者： Keith K. Khoo , Raymond S. Norton
DOI: 10.1002/9783527631841.CH11
关键词:
摘要: The native structures of proteins and peptides are stabilized by a number of interactions that dictate directly or indirectly the folding, conformation, and flexibility of the molecule. Most of these interactions, such as hydrogen bonds and hydrophobic interactions, are noncovalent and relatively weak. Covalent interactions, on the other hand, are generally stronger, and are thought to exert a greater influence on stability and conformation, particularly in peptides, which tend to have fewer and weaker hydrophobic interactions because of their …
sci-hub.se 参考文章(120)
Ki-Doo Choi, Seung-Gu Chang, Hang-Cheol Shin, Seung-Hwan Jang, Role of disulfide bonds in the structure and activity of human insulin. Molecules and Cells. ,vol. 16, pp. 323- 330 ,(2003)
Randal B. Bass, Scott L. Butler, Stephen A. Chervitz, Susan L. Gloor, Joseph J. Falke, Use of site-directed cysteine and disulfide chemistry to probe protein structure and dynamics: applications to soluble and transmembrane receptors of bacterial chemotaxis. Methods in Enzymology. ,vol. 423, pp. 25- 51 ,(2007) , 10.1016/S0076-6879(07)23002-2
C.M. Hewage, L. Jiang, J.A. Parkinson, R. Ramage, I.H. Sadler, Solution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modelling. Journal of Peptide Research. ,vol. 53, pp. 223- 233 ,(1999) , 10.1034/J.1399-3011.1999.00001.X
Andrew J. Doig, Dudley H. Williams, Is the hydrophobic effect stabilizing or destabilizing in proteins? The contribution of disulphide bonds to protein stability. Journal of Molecular Biology. ,vol. 217, pp. 389- 398 ,(1991) , 10.1016/0022-2836(91)90551-G
Wei-Hong Du, Yu-Hong Han, Fei-juan Huang, Juan Li, Cheng-Wu Chi, Wei-Hai Fang, Solution structure of an M-1 conotoxin with a novel disulfide linkage FEBS Journal. ,vol. 274, pp. 2596- 2602 ,(2007) , 10.1111/J.1742-4658.2007.05795.X
B A Katz, A Kossiakoff, The crystallographically determined structures of atypical strained disulfides engineered into subtilisin. Journal of Biological Chemistry. ,vol. 261, pp. 15480- 15485 ,(1986) , 10.1016/S0021-9258(18)66737-7
Protein folding coupled to disulphide bond formation. Biological Chemistry. ,vol. 378, pp. 731- 744 ,(1997) , 10.1515/BCHM.1997.378.8.731
Thomas E. Creighton, Nigel J. Darby, Johan Kemmink, The roles of partly folded intermediates in protein folding. The FASEB Journal. ,vol. 10, pp. 110- 118 ,(1996) , 10.1096/FASEBJ.10.1.8566531
S��lvia Bronsoms, Josep Villanueva, Francesc Canals, Enrique Querol, Francesc X. Aviles, Analysis of the effect of potato carboxypeptidase inhibitor pro‐sequence on the folding of the mature protein FEBS Journal. ,vol. 270, pp. 3641- 3650 ,(2003) , 10.1046/J.1432-1033.2003.03754.X
Olga Buczek, Daxiu Wei, Jeffrey J. Babon, Xiaodong Yang, Brian Fiedler, Ping Chen, Doju Yoshikami, Baldomero M. Olivera, Grzegorz Bulaj, Raymond S. Norton, Structure and sodium channel activity of an excitatory I1-superfamily conotoxin. Biochemistry. ,vol. 46, pp. 9929- 9940 ,(2007) , 10.1021/BI700797F