Joint Toxicity of Lead, Chromium, Cobalt and Nickel to Photobacterium phosphoreum at No Observed Effect Concentration

作者: Yaling Zeng , Lan Wang , Long Jiang , Xiaoyu Cai , Yu Li

DOI: 10.1007/S00128-015-1568-7

关键词:

摘要: Joint toxicity of Pb2+, Cr3+, Co2+ and Ni2+ toward Photobacterium phosphoreum (Ph. phosphoreum) at the no observed effect concentration (NOEC) was determined through a factorial experiment. A neural network model designed according to experimental results employed for prediction unary, binary, ternary quaternary combinations. The mechanism trends joint were interpreted by quantitative structure–activity relationship, Michaelis–Menten kinetic model, addition (CA) theory. Toxicity directly related covalent index (X m 2 r), binding reaction presented first zero order low high concentration, respectively, CA accurately predicted toxicity. Additionally, showed that concentrations heavy metals should be considered when conducting environment risk assessment.

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