Rate of utilization of glucose and `compartmentation' of α-oxoglutarate and glutamate in rat brain

摘要: 1. The rate of incorporation (14)C into pyruvate, alpha-oxoglutarate, lactate and glucose rat tissues was measured after the subcutaneous injection uniformly labelled glucose. 2. In brain specific radioactivities were similar to that alanine. liver radioactivity considerably higher than or 3. alpha-oxo acids lower those corresponding amino acids, alanine glutamate. These findings have been explained in relation metabolic compartments vivo. 4. approximate estimated utilization vivo is 0.96mumole/g. brain/min.