The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.
作者： Dipanjan Chowdhury , Paul J. Beresford , Pengcheng Zhu , Dong Zhang , Jung-Suk Sung
DOI: 10.1016/J.MOLCEL.2006.06.005
关键词:
摘要: … to verify the association of SET and TREX1 within cells by … SET peptide antisera also reacted with antisera to TREX1, … with TREX1, we wanted to determine whether SET affects TREX1 …
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sci-hub.se 参考文章(37)
Gillian M. Griffiths, Endocytosing the death sentence. Journal of Cell Biology. ,vol. 160, pp. 155- 156 ,(2003) , 10.1083/JCB.200212143
Denis Martinvalet, Pengcheng Zhu, Judy Lieberman, Granzyme A Induces Caspase-Independent Mitochondrial Damage, a Required First Step for Apoptosis Immunity. ,vol. 22, pp. 355- 370 ,(2005) , 10.1016/J.IMMUNI.2005.02.004
Masashi Morita, Gordon Stamp, Peter Robins, Anna Dulic, Ian Rosewell, Geza Hrivnak, Graham Daly, Tomas Lindahl, Deborah E. Barnes, Gene-Targeted Mice Lacking the Trex1 (DNase III) 3′→5′ DNA Exonuclease Develop Inflammatory Myocarditis Molecular and Cellular Biology. ,vol. 24, pp. 6719- 6727 ,(2004) , 10.1128/MCB.24.15.6719-6727.2004
Paul J. Beresford, Dong Zhang, David Y. Oh, Zusen Fan, Eric L. Greer, Melissa L. Russo, Madhuri Jaju, Judy Lieberman, Granzyme A Activates an Endoplasmic Reticulum-associated Caspase-independent Nuclease to Induce Single-stranded DNA Nicks Journal of Biological Chemistry. ,vol. 276, pp. 43285- 43293 ,(2001) , 10.1074/JBC.M108137200
Michael Bustin, Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Molecular and Cellular Biology. ,vol. 19, pp. 5237- 5246 ,(1999) , 10.1128/MCB.19.8.5237
Zusen Fan, Paul J. Beresford, Dong Zhang, Judy Lieberman, HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A. Molecular and Cellular Biology. ,vol. 22, pp. 2810- 2820 ,(2002) , 10.1128/MCB.22.8.2810-2820.2002
Judy Lieberman, The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal Nature Reviews Immunology. ,vol. 3, pp. 361- 370 ,(2003) , 10.1038/NRI1083
Colin Logie, Craig L. Peterson, Purification and biochemical properties of yeast SWI/SNF complex Methods in Enzymology. ,vol. 304, pp. 726- 741 ,(1999) , 10.1016/S0076-6879(99)04044-6
Wendy P. Osheroff, Hai Kwan Jung, William A. Beard, Samuel H. Wilson, Thomas A. Kunkel, The Fidelity of DNA Polymerase β during Distributive and Processive DNA Synthesis Journal of Biological Chemistry. ,vol. 274, pp. 3642- 3650 ,(1999) , 10.1074/JBC.274.6.3642
Dan J. Mazur, Fred W. Perrino, Structure and Expression of the TREX1 and TREX2 3′→5′ Exonuclease Genes Journal of Biological Chemistry. ,vol. 276, pp. 14718- 14727 ,(2001) , 10.1074/JBC.M010051200