Granzyme A Induces Caspase-Independent Mitochondrial Damage, a Required First Step for Apoptosis

作者: Denis Martinvalet , Pengcheng Zhu , Judy Lieberman

DOI: 10.1016/J.IMMUNI.2005.02.004

关键词:

摘要: … immune apoptotic pathways unaffected. For example, although granule exocytosis is the major pathway used by killer immune … for terminating the immune response and controlling the …

参考文章(59)
Santos A. Susin, Nathanael Larochette, Maurice Geuskens, Guido Kroemer, Purification of mitochondria for apoptosis assays. Methods in Enzymology. ,vol. 322, pp. 205- 208 ,(2000) , 10.1016/S0076-6879(00)22020-X
Donald D Newmeyer, Shelagh Ferguson-Miller, Mitochondria: Releasing power for life and unleashing the machineries of death Cell. ,vol. 112, pp. 481- 490 ,(2003) , 10.1016/S0092-8674(03)00116-8
Lianfa Shi, Xiaohe Yang, Christopher J. Froelich, Arnold H. Greenberg, Purification and use of granzyme B. Methods in Enzymology. ,vol. 322, pp. 125- 143 ,(2000) , 10.1016/S0076-6879(00)22013-2
Jay Parrish, Lily Li, Kristina Klotz, Duncan Ledwich, Xiaodong Wang, Ding Xue, Mitochondrial endonuclease G is important for apoptosis in C. elegans Nature. ,vol. 412, pp. 90- 94 ,(2001) , 10.1038/35083608
Michael R. Betts, Jason M. Brenchley, David A. Price, Stephen C. De Rosa, Daniel C. Douek, Mario Roederer, Richard A. Koup, Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation Journal of Immunological Methods. ,vol. 281, pp. 65- 78 ,(2003) , 10.1016/S0022-1759(03)00265-5
Anja Krippner, Akemi Matsuno-Yagi, Roberta A. Gottlieb, Bernard M. Babior, Loss of Function of Cytochrome c in Jurkat Cells Undergoing Fas-mediated Apoptosis Journal of Biological Chemistry. ,vol. 271, pp. 21629- 21636 ,(1996) , 10.1074/JBC.271.35.21629
Jie Yang, Xuesong Liu, Kapil Bhalla, Caryn Naekyung Kim, Ana Maria Ibrado, Jiyang Cai, Tsung-I Peng, Dean P Jones, Xiaodong Wang, Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked Science. ,vol. 275, pp. 1129- 1132 ,(1997) , 10.1126/SCIENCE.275.5303.1129
Paul J Beresford, Zhinan Xia, Arnold H Greenberg, Judy Lieberman, Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation. Immunity. ,vol. 10, pp. 585- 595 ,(1999) , 10.1016/S1074-7613(00)80058-8
Deqin Ma, Zhenlan Xing, Bin Liu, Nancy G. Pedigo, Stephen G. Zimmer, Zengliang Bai, Edith H. Postel, David M. Kaetzel, NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter. Journal of Biological Chemistry. ,vol. 277, pp. 1560- 1567 ,(2002) , 10.1074/JBC.M108359200
Douglas R Green, Guido Kroemer, The Pathophysiology of Mitochondrial Cell Death Science. ,vol. 305, pp. 626- 629 ,(2004) , 10.1126/SCIENCE.1099320