Effects on hemodynamics and left ventricular ejection fraction of intravenous be pridil for impaired left ventricular function secondary to coronary artery disease
作者： Martin A. Josephson , Tara Mody , Kristine Coyle , Bramah N. Singh
DOI: 10.1016/0002-9149(87)90982-9
关键词:
摘要: Abstract To define the hemodynamic effects of bepridil in patients with depressed left ventricular (LV) function, 22 an LV ejection fraction (EF) 0.45 or less were studied before, and after 2 mg/kg (n = 11) 4 intravenous bepridil. Maximal evident between 15 30 minutes drug infusion. After mg/kg, heart rate decreased 9 % (p
elsevier.com
sci-hub.se 参考文章(34)
K. A. Kane, E. Winslow, Antidysrhythmic and electrophysiological effects of a new antianginal agent, bepridil. Journal of Cardiovascular Pharmacology. ,vol. 2, pp. 193- 203 ,(1980) , 10.1097/00005344-198003000-00010
James M. Hopkins, Bramah N. Singh, Harvey S. Hecht, Martin A. Josephson, Reproducibility of equilibrium radionuclide ventriculography in patients with coronary artery disease: response of left ventricular ejection fraction and regional wall motion to supine bicycle exercise. American Heart Journal. ,vol. 104, pp. 567- 574 ,(1982) , 10.1016/0002-8703(82)90228-9
William Shapiro, Robert DiBianco, Udho Thadani, Comparative efficacy of 200, 300 and 400 mg of bepridil for chronic stable angina pectoris The American Journal of Cardiology. ,vol. 55, pp. C36- C42 ,(1985) , 10.1016/0002-9149(85)90804-5
Samuel Levy, Roland Cointe, Marc Metge, Gerard Faugere, Bernard Valeix, Raymond Gerard, Bepridil for recurrent sustained ventricular tachycardias: Assessment using electrophysiologic testing American Journal of Cardiology. ,vol. 54, pp. 579- 581 ,(1984) , 10.1016/0002-9149(84)90252-2
Uri Elkayam, Laura Weber, Behrooz Torkan, David Berman, Shahbudin H. Rahimtoola, Acute Hemodynamic Effect of Oral Nifedipine in Severe Chronic Congestive Heart Failure American Journal of Cardiology. ,vol. 52, pp. 1041- 1045 ,(1983) , 10.1016/0002-9149(83)90528-3
Randall M. Zusman, Donna M. Christensen, David J. Kanarek, Marla C. Kiess, Charles A. Boucher, Evaluation of bepridil for the treatment of angina pectoris: Evidence for preservation of left ventricular function The American Journal of Cardiology. ,vol. 55, pp. C30- C35 ,(1985) , 10.1016/0002-9149(85)90803-3
James A. Hill, John T. O'Brien, Elizabeth Scott, C.Richard Conti, Carl J. Pepine, Effects of Bepridil on exercise tolerance in chronic stable angina: A double-blind, randomized, placebo-controlled, crossover trial American Journal of Cardiology. ,vol. 53, pp. 679- 683 ,(1984) , 10.1016/0002-9149(84)90385-0
P A Ludbrook, A J Tiefenbrunn, F R Reed, B E Sobel, Acute hemodynamic responses to sublingual nifedipine: dependence on left ventricular function. Circulation. ,vol. 65, pp. 489- 498 ,(1982) , 10.1161/01.CIR.65.3.489
David C. Pang, Nick Sperelakis, Uptake of calcium antagonistic drugs into muscles as related to their lipid solubilities. Biochemical Pharmacology. ,vol. 33, pp. 821- 826 ,(1984) , 10.1016/0006-2952(84)90468-4
Christopher Y.C. Chew, Harvey S. Hecht, John T. Collett, Russell G. Mcallister, Bramah N. singh, Influence of severity of ventricular dysfunction on hemodynamic responses to intravenously administered verapamil in ischemic heart disease The American Journal of Cardiology. ,vol. 47, pp. 917- 922 ,(1981) , 10.1016/0002-9149(81)90194-6