Discrepancy Between Plasma C-Peptide and Insulin Response to Oral and Intravenous Glucose

摘要: Plasma insulin, proinsulin, and C-peptide responses to 25 g glucose orally intravenously administered were measured in 10 healthy males. insulin response was higher during the oral load accordance with “incretin” concept. However, actual amountof secreted, as by plasma response, similar two loads. The after not due crossreactivity proinsulin assay. These results suggest that an is at least partially a lower hepatic extraction of insulin.