A rapid and efficient synthesis of imidazo [1,2-a] and 1,2,4-triazolo [4,3-a]-piperazine car☐ylic acids.

作者: Gary A. McCort , Jean Claude Pascal

DOI: 10.1016/S0040-4039(00)60105-3

关键词:

摘要: Abstract A simple and general synthesis of novel cyclic α-amino acids by a route employing an easily accessable protected piperazine car☐ylic acid imino-ether is described.

参考文章(4)
George P. Claxton, J. Martin Grisar, Norbert L. Wiech, Cyclization of lactamimide ketones to imidazo(1,2-a)-azacycloalkanes with hypoglycemic activity. Journal of Medicinal Chemistry. ,vol. 17, pp. 364- 367 ,(1974) , 10.1021/JM00249A027
Robert V Hoffman, Kim Hwa-Ok, The preparation of 2-hydrazinyl esters in high optical purity from 2-sulfonyloxy esters Tetrahedron Letters. ,vol. 31, pp. 2953- 2956 ,(1990) , 10.1016/S0040-4039(00)88996-0
James A. Peliska, Marion H. O'Leary, Sulfuryl transfer catalyzed by pyruvate kinase. Biochemistry. ,vol. 28, pp. 1604- 1611 ,(1989) , 10.1021/BI00430A027