Are physicians prepared for whole genome sequencing? a qualitative analysis

摘要: Although the integration of whole genome sequencing (WGS) into standard medical practice is rapidly becoming feasible, physicians may be unprepared to use it. Primary care (PCPs) and cardiologists enrolled in a randomized clinical trial WGS received genomics education before completing semi-structured interviews. Themes about preparedness were identified transcripts through team-based consensus-coding. Data from 11 PCPs 9 suggested that primarily prepare themselves for widespread future. concerned their general genomic knowledge, while how interpret specific types results secondary findings. Both cohorts anticipated preparing extensively disclosing patients by using educational resources with which they already familiar, both making referrals genetics specialists as needed. A lack laboratory guidance, time pressures, standards contributed feeling unprepared. Physicians had specialty-specific concerns WGS. Findings identify policy changes could help feel more prepared, highlight providers all will need become familiar interpreting results.