Hot-Melt Extrusion of Ethylcellulose, Hypromellose and Polyethylene Oxide

Manish Munjal, Mahmoud A. ElSohly, Michael A. Repka, Polymeric Systems for Amorphous Δ9-Tetrahydrocannabinol Produced by a Hot-melt Method. Part II: Effect of Oxidation Mechanisms and Chemical Interactions on Stability Journal of Pharmaceutical Sciences. ,vol. 95, pp. 2473- 2485 ,(2006) , 10.1002/JPS.20711

E. Verhoeven, C. Vervaet, J.P. Remon, Xanthan gum to tailor drug release of sustained-release ethylcellulose mini-matrices prepared via hot-melt extrusion: in vitro and in vivo evaluation European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 63, pp. 320- 330 ,(2006) , 10.1016/J.EJPB.2005.12.004

Geert Verreck, Annelies Decorte, Hongbo Li, David Tomasko, Albertina Arien, Jef Peeters, Patrick Rombaut, Guy Van den Mooter, Marcus E. Brewster, The effect of pressurized carbon dioxide as a plasticizer and foaming agent on the hot melt extrusion process and extrudate properties of pharmaceutical polymers Journal of Supercritical Fluids. ,vol. 38, pp. 383- 391 ,(2006) , 10.1016/J.SUPFLU.2005.11.022

Alazar N. Ghebremeskel, Chandra Vemavarapu, Mayur Lodaya, Use of Surfactants as Plasticizers in Preparing Solid Dispersions of Poorly Soluble API: Stability Testing of Selected Solid Dispersions Pharmaceutical Research. ,vol. 23, pp. 1928- 1936 ,(2006) , 10.1007/S11095-006-9034-1

Ping Gao, Michael E. Guyton, Tiehua Huang, Juliane M. Bauer, Kevin J. Stefanski, Qun Lu, Enhanced oral bioavailability of a poorly water soluble drug PNU-91325 by supersaturatable formulations Drug Development and Industrial Pharmacy. ,vol. 30, pp. 221- 229 ,(2004) , 10.1081/DDC-120028718

Xin Zheng, Rui Yang, Yu Zhang, Zhijun Wang, Xing Tang, Liangyuan Zheng, Part II: Bioavailability in Beagle Dogs of Nimodipine Solid Dispersions Prepared by Hot-Melt Extrusion Drug Development and Industrial Pharmacy. ,vol. 33, pp. 783- 789 ,(2007) , 10.1080/03639040601050205

Kazunari Yamashita, Toshiomi Nakate, Kazuto Okimoto, Atsuo Ohike, Yuji Tokunaga, Rinta Ibuki, Kazutaka Higaki, Toshikiro Kimura, Establishment of new preparation method for solid dispersion formulation of tacrolimus. International Journal of Pharmaceutics. ,vol. 267, pp. 79- 91 ,(2003) , 10.1016/J.IJPHARM.2003.07.010

Suneela Prodduturi, Kevin L. Urman, Joshua U. Otaigbe, Michael A. Repka, Stabilization of hot-melt extrusion formulations containing solid solutions using polymer blends Aaps Pharmscitech. ,vol. 8, pp. 1- ,(2007) , 10.1208/PT0802050

Christopher R. Young, Caroline Dietzsch, Matteo Cerea, Thomas Farrell, Kurt A. Fegely, Ali Rajabi-Siahboomi, James W. McGinity, Physicochemical characterization and mechanisms of release of theophylline from melt-extruded dosage forms based on a methacrylic acid copolymer International Journal of Pharmaceutics. ,vol. 301, pp. 112- 120 ,(2005) , 10.1016/J.IJPHARM.2005.05.025

Praveen K. Mididoddi, Michael A. Repka, Characterization of hot-melt extruded drug delivery systems for onychomycosis. European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 66, pp. 95- 105 ,(2007) , 10.1016/J.EJPB.2006.08.013