Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome.

作者: Emily K. Osterweil , Shih-Chieh Chuang , Alexander A. Chubykin , Michael Sidorov , Riccardo Bianchi

DOI: 10.1016/J.NEURON.2012.01.034

关键词:

摘要: … Our results show that lovastatin can indeed correct excessive protein synthesis and prevent the emergence of epileptiform activity in the Fmr1 KO hippocampus in vitro and can protect …

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