Increased Diacylglycerols Characterize Hepatic Lipid Changes in Progression of Human Nonalcoholic Fatty Liver Disease; Comparison to a Murine Model
作者： D. Lee Gorden , Pavlina T. Ivanova , David S. Myers , J. Oliver McIntyre , Michael N. VanSaun
DOI: 10.1371/JOURNAL.PONE.0022775
关键词:
摘要: … NAFLD have also shown the importance of the phosphatidylcholine (PC)/phosphatidylethanolamine (PE) ratio on liver disease progression … signaling and in the progression of NAFLD. …
harvard.edu
elsevier.com
paperity.org参考文章(35)
Ismo Mattila, Tuulikki Seppänen-Laakso, Tapani Suortti, Matej Orešič, Application of lipidomics and metabolomics to the study of adipose tissue. Methods of Molecular Biology. ,vol. 456, pp. 123- 130 ,(2008) , 10.1007/978-1-59745-245-8_9
Michael J. O. Wakelam, Trevor R. Pettitt, Janet M. Lord, Paul Webb, Elizabeth M. Deacon, Timothy Cross, Hema Chahal, Generation of diacylglycerol molecular species through the cell cycle: a role for 1-stearoyl, 2-arachidonyl glycerol in the activation of nuclear protein kinase C-βII at G2/M Journal of Cell Science. ,vol. 115, pp. 983- 989 ,(2002) , 10.1242/JCS.115.5.983
C Cascales, E H Mangiapane, D N Brindley, Oleic acid promotes the activation and translocation of phosphatidate phosphohydrolase from the cytosol to particulate fractions of isolated rat hepatocytes Biochemical Journal. ,vol. 219, pp. 911- 916 ,(1984) , 10.1042/BJ2190911
Pavlina T. Ivanova, Stephen B. Milne, Mark O. Byrne, Yun Xiang, H. Alex Brown, Glycerophospholipid identification and quantitation by electrospray ionization mass spectrometry. Methods in Enzymology. ,vol. 432, pp. 21- 57 ,(2007) , 10.1016/S0076-6879(07)32002-8
Quentin M. Anstee, Robert D. Goldin, Mouse models in non-alcoholic fatty liver disease and steatohepatitis research International Journal of Experimental Pathology. ,vol. 87, pp. 1- 16 ,(2006) , 10.1111/J.0959-9673.2006.00465.X
Yasutomi Nishizuka, Protein kinase C and lipid signaling for sustained cellular responses. The FASEB Journal. ,vol. 9, pp. 484- 496 ,(1995) , 10.1096/FASEBJ.9.7.7737456
Laxman Yetukuri, Mikko Katajamaa, Gema Medina-Gomez, Tuulikki Seppänen-Laakso, Antonio Vidal-Puig, Matej Orešič, Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis. BMC Systems Biology. ,vol. 1, pp. 12- 12 ,(2007) , 10.1186/1752-0509-1-12
Stephen B. Milne, Pavlina T. Ivanova, Michelle D. Armstrong, David S. Myers, Jovana Lubarda, Yulia V. Shulga, Matthew K. Topham, H. Alex Brown, Richard M. Epand, Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase. Biochemistry. ,vol. 47, pp. 9372- 9379 ,(2008) , 10.1021/BI800492C
Stephen Milne, Pavlina Ivanova, Jeffrey Forrester, H. Alex Brown, Lipidomics: an analysis of cellular lipids by ESI-MS. Methods. ,vol. 39, pp. 92- 103 ,(2006) , 10.1016/J.YMETH.2006.05.014
Hannah L. Callender, Jeffrey S. Forrester, Pavlina Ivanova, Anita Preininger, Stephen Milne, H. Alex Brown, Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm. Analytical Chemistry. ,vol. 79, pp. 263- 272 ,(2007) , 10.1021/AC061083Q