Receptor for natural killer and non-specific cytotoxic cells

摘要: The present invention encompasses a receptor protein on the surface of natural killer cells (NK cells) and non-specific cytotoxic (NCC) which is involved in lysis target bearing an antigen recognized by monoclonal antibodies bind to are useful their identification purification, methods for altering NK cell-mediated cells. (mAbs) were prepared cell fusions between spleen from mice immunized with either catfish (anti-receptor antibodies) myeloma was purified solubilized flow cytometry using antigen-antibody complexing techniques, immune precipitation or affinity chromatography Affigel-10™ Con A Sepharose mAbs. Using mAbs but do not inhibit produces same results as lysis. Analysis 12% SDS shows that it dimeric molecule consisting 41,000 38,000 D proteins.