Women and Cardiovascular Heart Disease: Clinical Implications From the Women’s Ischemia Syndrome Evaluation (WISE) Study : Are We Smarter?

作者: Amir Lerman , George Sopko

DOI: 10.1016/J.JACC.2004.10.083

关键词:

摘要: Review of the trend in cardiovascular disease mortality for males and females clearly demonstrated that whereas shows a decline this is not observed females. Multiple important reports emerged from initial phases Women’s Ischemic Syndrome Evaluation (WISE) study may have significant clinical implications our approach to women. The data derived WISE certainly provided information understanding women with disease. presentation be different, gender-oriented questionnaire enhance diagnosis. In multivariable model, low hemoglobin was associated significantly higher risk adverse outcomes. factor assessment profiles are coronary artery different. Based on studies study, metabolic syndrome leading major Moreover, further support concept mechanism ischemia localized microvascular arteries. Therefore, diagnoses dysfunction or endothelial should considered chest pain who do obstructive It advantageous add such diagnostic tests when conventional nondiagnostic. A revised designed tested based these findings.

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