Random pentapolymer for treatment of autoimmune diseases
作者： Ehud Marom , Shai Rubnov
DOI:
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摘要: The present invention provides a synthetic polypeptide which is random pentapolymer or salt thereof, comprising alanine, glutamic acid, lysine, tyrosine and phenylalanine, useful for the treatment of autoimmune diseases and, in particular multiple sclerosis (MS). copolymer are randomly polymerized into polypeptide, thereby forming copolymer, thereof based part on unexpected finding that novel shows oral bioavailability, an advantageous release profile when formulated depot drug delivery system synergistic activity combined with additional therapeutic agent. According to first aspect, linear phenylalanine.
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