Inherited partial trisomy #15 complicated by neuroblastoma
作者： Warren G. Sanger , Janet Howe , Renee Fordyce , David T. Purtilo
DOI: 10.1016/0165-4608(84)90109-2
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摘要: Abstract The proband in this study had multiple congenital malformations and a constitutional 46,XY,−13,+der(13),t(13;15)(q34;q23)mat chromosome complement. A bone marrow aspirate revealed neuroblastoma, cytogenetic studies on tumor cells revealed, addition to the partial trisomy #15 probable monosomy #13, hypotetraploidy with mean number of 82–84, including 3 or 4 copies each autosome, 2 X chromosomes, no Y chromosome, marker. Translocations involving chromosomes #1, #2, #3, #7, #14 were present, along double minutes. possibility that inherited (and/or #13 monosomy) predisposed neuroblastoma additional changes is discussed.
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sci-hub.se 参考文章(20)
D. T. Purtilo, L. Paquin, T. Gindhart, Genetics of neoplasia--impact of ecogenetics on oncogenesis. A review. American Journal of Pathology. ,vol. 91, pp. 609- 688 ,(1978)
Fred Rosner, Stanley L. Lee, Down's syndrome and acute leukemia: Myeloblastic or lymphoblastic? The American Journal of Medicine. ,vol. 53, pp. 203- 218 ,(1972) , 10.1016/0002-9343(72)90130-1
Avery A. Sandberg, The chromosomes in human cancer and leukemia ,(1990)
Baren A, Wakonig-Vaartaja T, Koss Lg, Helson L, Murphy Ml, Cytogenetic observations in children with neuroblastoma. Pediatrics. ,vol. 47, pp. 839- 843 ,(1971)
Uta Francke, Vincent M. Riccardi, Ann C. Smith, Eva Sujansky, Chromosomal imbalance in the Aniridia-Wilms' tumor association: 11p interstitial deletion. Pediatrics. ,vol. 61, pp. 604- 610 ,(1978)
MURRAY FEINGOLD, FAMILIAL NEUROBLASTOMA AND TRISOMY 13 Archives of Pediatrics & Adolescent Medicine. ,vol. 121, pp. 451- 451 ,(1971) , 10.1001/ARCHPEDI.1971.02100160121024
N C Nevin, J A Dodge, I V Allen, Two cases of trisomy D associated with adrenal tumours. Journal of Medical Genetics. ,vol. 9, pp. 119- 122 ,(1972) , 10.1136/JMG.9.1.119
Andrew J. Cohen, Frederick P. Li, Solomon Berg, David J. Marchetto, Shien Tsai, Stephen C. Jacobs, Robert S. Brown, Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation New England Journal of Medicine. ,vol. 301, pp. 592- 595 ,(1979) , 10.1056/NEJM197909133011107
G. M. Brodeur, G. S. Sekhon, M. N. Goldstein, Chromosomal aberrations in human neuroblastomas. Cancer. ,vol. 40, pp. 2256- 2263 ,(1977) , 10.1002/1097-0142(197711)40:5<2256::AID-CNCR2820400536>3.0.CO;2-1
U. Francke, Retinoblastoma and chromosome 13. Cytogenetic and Genome Research. ,vol. 16, pp. 131- 134 ,(1976) , 10.1159/000130573