A prospective study for the association of Helicobacter pylori infection to a multidimensional measure for recurrent abdominal pain in children.

摘要: Background:  There is a controversial association between Helicobacter pylori infection and recurrent abdominal pain (RAP) in childhood inconsistent information on specific symptomatology of the infection. Aims:  To examine prevalence H. pylori among children with RAP compared to asymptomatic children. Methods:  Two prospective studies were conducted. The first study enrolled 223 diagnosed from two pediatric gastroenterology clinics Houston, Texas. Children qualified if they identified by their physician as having RAP. A new multidimensional measure for (MM-RAP) consisting four scales (pain intensity scale, symptoms disability satisfaction scale) was administered each child/parent. second 330 same community who did not have any upper gastrointestinal symptoms. Symptomatic underwent 13C-urea breath testing. Results:  In study, H. 11% fell age 20% at age ≤ 5 years 7% > 10 years (OR = 2.7, 95% CI = 0.7–11.2). no mother's educational level prevalence; (12% whose mothers completed college versus those had elementary school, p = .8). No relationship found mean scores scales. 17% increased ≤ 5 years 40% (OR = 5.4, CI = 2.0–13.8). inversely correlated (OR = 3.0, CI = 2.2–6.1, p < .01). Conclusions:  epidemiologic patterns differed significantly symptomatic children. Younger suffering are more likely be infected than older complaint, suggesting that early acquisition may manifest lead clinic visits.