Stability of executive functions in first episode psychosis: One year follow up study.
作者： Beathe Haatveit , Anja Vaskinn , Kjetil S. Sundet , Jimmy Jensen , Ole A. Andreassen
DOI: 10.1016/J.PSYCHRES.2015.05.060
关键词:
摘要: Executive functioning is a multi-dimensional construct covering several sub-processes. The aim of this study was to determine whether executive functions, indexed by broad range measures remain stable in first episode psychosis (FEP) over time. Eighty-two patients and 107 age gender matched healthy controls were assessed on five subdomains functioning; working memory, fluency, flexibility, inhibitory control at baseline 1 year follow-up. Results showed that performed significantly poorer than all both assessment points. In general functions remained from follow-up, although groups improved flexibility. phonemic slight improvement while decline. Investigation individual trajectories revealed some fluctuations time, but mainly supports the group level findings. implications these results are discussed.
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AINA HOLMÉN, MONICA JUUHL-LANGSETH, RUNE THORMODSEN, KJETIL SUNDET, INGRID MELLE, BJØRN RISHOVD RUND, Executive function tests in early-onset psychosis: which one to choose? Scandinavian Journal of Psychology. ,vol. 53, pp. 200- 205 ,(2012) , 10.1111/J.1467-9450.2012.00940.X
Susan R. McGurk, Kim T. Mueser, Cognitive functioning and employment in severe mental illness Journal of Nervous and Mental Disease. ,vol. 191, pp. 789- 798 ,(2003) , 10.1097/01.NMD.0000100921.31489.5A
Bjorn Rund, None, Is there a degenerative process going on in the brain of people with schizophrenia? Frontiers in Human Neuroscience. ,vol. 3, pp. 36- 36 ,(2009) , 10.3389/NEURO.09.036.2009
Delbert G Robinson, Margaret G Woerner, Jose Ma.J Alvir, Robert M Bilder, Gregory A Hinrichsen, Jeffrey A Lieberman, Predictors of medication discontinuation by patients with first-episode schizophrenia and schizoaffective disorder. Schizophrenia Research. ,vol. 57, pp. 209- 219 ,(2002) , 10.1016/S0920-9964(01)00312-7
Julie Henry, John Crawford, A meta-analytic review of verbal fluency deficits in schizophrenia relative to other neurocognitive deficits. Cognitive Neuropsychiatry. ,vol. 10, pp. 1- 33 ,(2005) , 10.1080/13546800344000309
Christopher R Bowie, Philip D Harvey, Cognitive deficits and functional outcome in schizophrenia. Neuropsychiatric Disease and Treatment. ,vol. 2, pp. 531- 536 ,(2006) , 10.2147/NEDT.2006.2.4.531
Maria Ekerholm, Svala Firus Waltersson, Thomas Fagerberg, Erik Söderman, Lars Terenius, Ingrid Agartz, Erik Gunnar Jönsson, Håkan Nyman, Neurocognitive function in long-term treated schizophrenia: a five-year follow-up study. Psychiatry Research-neuroimaging. ,vol. 200, pp. 144- 152 ,(2012) , 10.1016/J.PSYCHRES.2012.05.008
Sophia Frangou, Cognitive function in early onset schizophrenia: a selective review Frontiers in Human Neuroscience. ,vol. 3, pp. 79- 79 ,(2009) , 10.3389/NEURO.09.079.2009
M Mayoral, A Zabala, O Robles, I Bombin, P Andres, M Parellada, D Moreno, M Graell, O Medina, C Arango, Neuropsychological functioning in adolescents with first episode psychosis: a two-year follow-up study. European Psychiatry. ,vol. 23, pp. 375- 383 ,(2008) , 10.1016/J.EURPSY.2008.01.1420
Monica Aas, Paola Dazzan, Valeria Mondelli, Ingrid Melle, Robin M. Murray, Carmine M. Pariante, A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress and inflammation Frontiers in Psychiatry. ,vol. 4, pp. 182- 182 ,(2014) , 10.3389/FPSYT.2013.00182