Multiphase catalytic reactor engineering and design for pharmaceuticals and fine chemicals

摘要: A review of recent developments in multiphase catalytic processes for the manufacture pharmaceutical and fine chemicals, an overview reaction engineering principles needed analysis local overall rate reactor design interpretation performance is presented. The first section gives applications pharmaceuticals chemicals where heterogeneous homogeneous catalyzed chemistries have been identified that are more efficient represent safer operation with decreased environmental impact when compared to existing processes. next three sections describe a scheme classification various types reactions typically encountered, along distinguishing features these commonly used types. This followed by describing reaction, including summary typical models evaluation intrinsic kinetics, incorporation transport-kinetic interactions, methods identification controlling regime assessment relative contribution transport effects. two set forth basic types, mechanically agitated reactors bubble column reactors. brief correlations estimation mass transfer coefficients gas-liquid liquid-liquid systems also given. final devoted key issues occur chemical processes, some thoughts on future needs challenges.