Oxytocin Secretion Is Associated with Severity of Disordered Eating Psychopathology and Insular Cortex Hypoactivation in Anorexia Nervosa
作者： Elizabeth A. Lawson , Laura M. Holsen , McKale Santin , Erinne Meenaghan , Kamryn T. Eddy
DOI: 10.1210/JC.2012-1702
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摘要: Context: Animal data suggest that oxytocin is a satiety hormone. We have demonstrated anorexia nervosa (anorexia), disorder characterized by food restriction, low weight, and hypoleptinemia, associated with decreased nocturnal secretion. also reported functional magnetic resonance imaging (fMRI) hypoactivation in brain regions involved motivation. The relationships between oxytocin, food-motivation neurocircuitry, disordered eating psychopathology not been investigated humans. Objective: objective of the study was to determine whether response feeding differs from healthy women establish relationship secretion neurocircuitry. Design: This cross-sectional study. Setting: conducted at clinical research center. Participants: Participants included 35 women: 13 (AN), nine weight-recovered (ANWR), ...
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