Intranasal oxytocin attenuates attentional bias for eating and fat shape stimuli in patients with anorexia nervosa

摘要: We examined the impact of oxytocin on attentional processes for eating, shape, and weight stimuli in patients with anorexia nervosa (AN). A double-blind, placebo-controlled within-subject crossover design was used. Intranasal or placebo followed by a visual probe detection task food, weight, shape images administered to 64 female subjects: 31 AN 33 control students. The group showed significant reductions biases toward eating-related (p=0.030, d=0.516) negative (p=0.015, d=0.498) under influence intranasal oxytocin. effect correlated autistic spectrum traits group. Oxytocin had no amount juice consumed either results this study suggest that attenuates vigilance eating fat AN. Further studies using as form intervention are needed.