Synthesis, Characterization and Luminescence Sensitivity with Variance in pH, DNA and BSA Binding Studies of Ru(II) Polypyridyl Complexes
作者： Ravi Kumar Vuradi , Srishailam Avudoddi , Venkat Reddy Putta , Laxma Reddy Kotha , Praveen Kumar Yata
DOI: 10.1007/S10895-017-2029-Y
关键词:
摘要: Three ruthenium(II) polypyridyl complexes, [Ru(phen)2(mip)](ClO4)2 (1) (phen =1,10-Phenanthroline), [Ru(bpy)2(mip)](ClO4)2 (2) (bpy = 2,2’bipyridyl) and [Ru(dmb)2(mip)](ClO4)2 (3) (dmb = 4, 4′-dimethyl 2, 2′-bipyridine), were synthesized with an intercalative ligand mip (2-morpholino-1H-imidazo[4,5-f][1, 10]phenanthroline) characterized by 1H, 13C–NMR, IR, UV-vis, mass spectra elemental analysis. pH effect, ion selectivity (cations, anions) solvent sensitivity of complexes studied. The interaction these DNA was performed using absorption, emission spectroscopy viscosity measurements. experimental results indicated that the two interacted calf thymus (CT-DNA) mode. BSA (Bovine Serum Albumin) protein binding studied UV-visible fluorescence techniques. capacity explained theoretically molecular docking method.
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