Detection of minor populations of drug-resistant HIV-1 in acute seroconverters.

作者: Karin J Metzner , Pia Rauch , Hauke Walter , Christoph Boesecke , Bernhard Zöllner

DOI: 10.1097/01.AIDS.0000189878.97480.ED

关键词:

摘要: … minor viral variants can emerge as the major viral population [7,8] . By using a methodology that allows the quantification of minor … as minor viral species in acutely HIV-infected patients. …

参考文章(24)
Annemarie M Wensing, Charles A Boucher, Worldwide transmission of drug-resistant HIV. Aids Reviews. ,vol. 5, pp. 140- 155 ,(2003)
Rob Schuurman, Lisa Demeter, Patricia Reichelderfer, Jolanda Tijnagel, Tom de Groot, Charles Boucher, Worldwide evaluation of DNA sequencing approaches for identification of drug resistance mutations in the human immunodeficiency virus type 1 reverse transcriptase. Journal of Clinical Microbiology. ,vol. 37, pp. 2291- 2296 ,(1999) , 10.1128/JCM.37.7.2291-2296.1999
M. Egger, B. Hirschel, P. Francioli, P. Sudre, M. Wirz, M. Flepp, M. Rickenbach, R. Malinverni, P. Vernazza, M. Battegay, Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study. Swiss HIV Cohort Study. BMJ. ,vol. 315, pp. 1194- 1199 ,(1997) , 10.1136/BMJ.315.7117.1194
Amalio Telenti, Manuel Battegay, Thomas Perneger, Pietro Vernazza, Sabine Yerly, Bernard Hirschel, Hansjakob Furrer, Martin Rickenbach, Jean-Philippe Chave, Markus Flepp, Stéphanie Jost, Laurent Kaiser, Luc Perrin, Martin Gebhardt, Marie-Charlotte Bernard, Philippe Burgisser, Bruno Chanzy, Infrequent transmission of HIV-1 drug-resistant variants. Antiviral Therapy. ,vol. 9, pp. 375- 384 ,(2004)
KALACHAR SURYANARAYANA, THERESA A. WILTROUT, GABRIELA M. VASQUEZ, VANESSA M. HIRSCH, JEFFREY D. LIFSON, Plasma SIV RNA Viral Load Determination by Real-Time Quantification of Product Generation in Reverse Transcriptase-Polymerase Chain Reaction AIDS Research and Human Retroviruses. ,vol. 14, pp. 183- 189 ,(1998) , 10.1089/AID.1998.14.183
Jason D Barbour, Frederick M Hecht, Terri Wrin, Teri J Liegler, Clarissa A Ramstead, Michael P Busch, Mark R Segal, Christos J Petropoulos, Robert M Grant, Persistence of primary drug resistance among recently HIV-1 infected adults. AIDS. ,vol. 18, pp. 1683- 1689 ,(2004) , 10.1097/01.AIDS.0000131391.91468.FF
Susanne Duwe, Monika Brunn, Doris Altmann, Osamah Hamouda, Barbara Schmidt, Hauke Walter, Georg Pauli, Claudia K??cherer, Frequency of genotypic and phenotypic drug-resistant HIV-1 among therapy-naive patients of the German Seroconverter Study. Journal of Acquired Immune Deficiency Syndromes. ,vol. 26, pp. 266- 273 ,(2001) , 10.1097/00042560-200103010-00010
Rob Schuurman, Donald Brambilla, Tom de Groot, Diana Huang, Sally Land, James Bremer, Ireen Benders, Charles A.B. Boucher, Underestimation of HIV type 1 drug resistance mutations: results from the ENVA-2 genotyping proficiency program. AIDS Research and Human Retroviruses. ,vol. 18, pp. 243- 248 ,(2002) , 10.1089/088922202753472801
R. T. Gandhi, A. Wurcel, E. S. Rosenberg, M. N. Johnston, N. Hellmann, M. Bates, M. S. Hirsch, B. D. Walker, Progressive reversion of human immunodeficiency virus type 1 resistance mutations in vivo after transmission of a multiply drug-resistant virus. Clinical Infectious Diseases. ,vol. 37, pp. 1693- 1698 ,(2003) , 10.1086/379773
C.R. Newton, A. Graham, L.E. Heptinstall, S.J. Powell, C Summers, N. Kalsheker, J.C. Smith, A.F. Markham, Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS) Nucleic Acids Research. ,vol. 17, pp. 2503- 2516 ,(1989) , 10.1093/NAR/17.7.2503