Platelet survival in rats with spontaneous diabetes mellitus.
作者： R L Kinlough-Rathbone , J F Mustard , P D Winocour
DOI: 10.5555/URI:PII:0022214387901193
关键词:
摘要: The results from these studies show that platelet survival is prolonged in spontaneously diabetic rats. These confirm those obtained rats 4 weeks after they had been made by an injection of streptozocin. Platelet was also the nondiabetic littermates (normoglycemic) indicating effect on may be unrelated to blood glucose concentrations. mechanism responsible for this prolongation unclear. Thus, under experimental conditions which do not have vascular disease, diabetes associated with survival. Vascular injury induced indwelling aortic catheters shortened same extent rats, their littermates, and controls. There a significantly greater accumulation platelets damaged aortas animals than or This could result increased decreased turnover vessel wall; macroscopic thrombi were observed any groups catheters. We conclude previously streptozocin-induced attributable state some other drug chronic absence disease necessarily
sci-hub.st 参考文章(21)
JP Greenberg, MA Packham, MA Guccione, ML Rand, HJ Reimers, JF Mustard, Survival of rabbit platelets treated in vitro with chymotrypsin, plasmin, trypsin, or neuraminidase. Blood. ,vol. 53, pp. 916- 927 ,(1979) , 10.1182/BLOOD.V53.5.916.BLOODJOURNAL535916
P.D. Winocour, J.A. Colwell, Reduced platelet-mediated and enhanced leukocyte-mediated fibrinolysis in experimentally induced diabetes in rats. Journal of Laboratory and Clinical Medicine. ,vol. 105, pp. 613- ,(1985)
P D Winocour, R L Kinlough-Rathbone, M Richardson, J F Mustard, Reversal of shortened platelet survival in rats by the antifibrinolytic agent, epsilon aminocaproic acid. Journal of Clinical Investigation. ,vol. 71, pp. 159- 164 ,(1983) , 10.1172/JCI110745
George Drivas, Nigel Wardle, Reticuloendothelial cell dysfunction in diabetes and hyperlipidemia. Metabolism-clinical and Experimental. ,vol. 27, pp. 1533- 1538 ,(1978) , 10.1016/S0026-0495(78)80026-2
R.C. Paton, Platelet survival in diabetes mellitus using an aspirin-labelling technique Thrombosis Research. ,vol. 15, pp. 793- 802 ,(1979) , 10.1016/0049-3848(79)90188-9
R. B. Wilson, J. M. Martin, W. S. Hartroft, Evaluation of the Relative Pathogenic Roles of Diabetes and Serum Cholesterol Levels in the Development of Cardiovascular Lesions in Rats Diabetes. ,vol. 16, pp. 71- 82 ,(1967) , 10.2337/DIAB.16.2.71
N. G. Ardlie, M. A. Packham, J. F. Mustard, Adenosine Diphosphate-induced Platelet Aggregation in Suspensions of Washed Rabbit Platelets British Journal of Haematology. ,vol. 19, pp. 7- 17 ,(1970) , 10.1111/J.1365-2141.1970.TB01596.X
E. Schneider, U. Fuchs, G. Schneider, W. Helbig, Phagocytosis of inert particles in the reticuloendothelial system in rats with experimental insulinopenic diabetes Experimentelle Pathologie. ,vol. 18, pp. 75- 79 ,(1980) , 10.1016/S0014-4908(80)80073-1
E.A. Murphy, M.E. Francis, D.R. Bulling, Estimation of blood platelet survival—V. A method for the analysis of population data Journal of Chronic Diseases. ,vol. 26, pp. 797- 815 ,(1973) , 10.1016/0021-9681(73)90014-3
P D Winocour, M Cattaneo, D Somers, M Richardson, R L Kinlough-Rathbone, J F Mustard, Platelet survival and thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 2, pp. 458- 466 ,(1982) , 10.1161/01.ATV.2.6.458