Recent results of multimodal therapy of gastric lymphoma.

作者: Man H. Shiu , Lourdes Z. Nisce , Antonio Pinna , David J. Straus , Michael Tome

DOI: 10.1002/1097-0142(19861001)58:7<1389::AID-CNCR2820580702>3.0.CO;2-Y

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摘要: The efficacy of multimodality treatment gastric lymphoma was examined in a retrospective study 46 patients treated at the Memorial Sloan-Kettering Cancer Center from 1971 to 1982. principal plan consisted surgical resection (n = 36) where feasible, followed by radiation therapy whole abdomen 23) with boosting dose stomach-bed 3700 cGy, and/or chemotherapy using mainly CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) regimen as an adjuvant 7), or plus other drugs for advanced disease. median follow-up time 61 months (range, 30 14 years). There no operative mortality. No patient developed known relapse after and total abdominal irradiation, none suffered relapses chemotherapy, Stages I-E II-E. At 5 years, estimated survival rate 95%, 78%, 25%, respectively 20), II-E 9) IV 17). results Stage resectable tumors were significantly improved (P less than 0.05 0.1 respectively) over those similar 1949 1970.

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