High MET amplification level as a resistance mechanism to osimertinib (AZD9291) in a patient that symptomatically responded to crizotinib treatment post-osimertinib progression

作者: Sai-Hong Ignatius Ou , Nikita Agarwal , Siraj M. Ali

DOI: 10.1016/J.LUNGCAN.2016.05.015

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摘要: … Planchard et al. were not able to demonstrate if MET amplification was absent prior to … in the tumor texture after tumor blockade with single agent crizotinib, a MET inhibitor [12]. However…

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