REM Sleep and the Early Development of Posttraumatic Stress Disorder
作者： Thomas A. Mellman , Victoria Bustamante , Ana I. Fins , Wilfred R. Pigeon , Bruce Nolan
DOI: 10.1176/APPI.AJP.159.10.1696
关键词:
摘要: Objective: The potential for chronicity and treatment resistance once posttraumatic stress disorder (PTSD) has become established stimulated interest in understanding the early pathogenesis of disorder. Arousal regulation memory consolidation appear to be important determining development PTSD; both are functions sleep. Sleep findings from patients with chronic PTSD complex somewhat contradictory, data acute phase quite limited. aim present study was obtain polysomnographic recordings during an period after life-threatening experiences injury relate measures sleep duration maintenance timing, intensity, continuity REM PTSD. Method: Twenty-one injured subjects meeting criteria received at least one recording close time medical/surgical stabilization within a month injury. symptoms were assessed concurrently 6 weeks later. compared among without significant follow-up 10 noninjured comparison also correlated severity. Results: There more wake onset injured, trauma-exposed than subjects. Development associated shorter average before stage change periods Conclusions: traumatic is fragmented pattern
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