Re: Sunscreen Use and Duration of Sun Exposure: a Double-Blind, Randomized Trial

摘要: Background: In epidemiologic studies, sunscreen use is associated with increased risk of cutaneous melanoma, basal cell skin cancer, and higher numbers nevi. It has been proposed that sunscreens may encourage prolonged sun exposure because they delay sunburn occurrence. We examined whether, under habitual conditions use, the sun-protection factor (SPF) had an influence on sun-exposure duration. Methods: Before 1997 summer holidays, we randomly assigned 87 French Swiss participants who were 18-24 years age to receive SPF 10 or 30 sunscreen. Neither medical personnel nor study aware their assignment. Participants asked complete daily records exposure. To avoid influencing recreational habits participants, no recommendation was made about protection. Furthermore, told trial end point number pigmented lesions before after holidays. One subject lost follow-up. All statistical tests two-sided. Results: The (n = 44) 42) groups equivalent mean holiday durations (19.4 days versus 20.2 days) quantities used (72.3 g 71.6 g). cumulative exposures for two 58.2 hours 72.6 hours, respectively (P .011). sunbathing 2.6 3.1 .0013), and, outdoor activities, 3.6 3.8 .62). There difference in experience between groups. Conclusions: Use seems increase duration young white Europeans.