Chimerism Testing by Quantitative PCR Using Indel Markers
作者： Ketevan Gendzekhadze , Laima Gaidulis , David Senitzer
DOI: 10.1007/978-1-62703-493-7_11
关键词:
摘要: Engraftment monitoring is critical for patients after Hematopoietic Stem Cell Transplantation (HSCT). Complete donor chimerism the goal; therefore, early detection of rejection and relapse crucial guiding patient post HSCT treatment. Quantitative PCR testing has been reported to be highly sensitive. In this chapter we discuss quantitative (qPCR) method using 34 Indel (Insertion Deletion) genetic markers spread over 20 different chromosomes.
springer.com
sci-hub.se 参考文章(7)
DM Mickelson, L Sproat, R Dean, R Sobecks, L Rybicki, M Kalaycio, B Pohlman, J Sweetenham, S Andresen, B Bolwell, EA Copelan, None, Comparison of donor chimerism following myeloablative and nonmyeloablative allogeneic hematopoietic SCT. Bone Marrow Transplantation. ,vol. 46, pp. 84- 89 ,(2011) , 10.1038/BMT.2010.55
Aldemar Montero, Bipin N. Savani, Roger Kurlander, Elizabeth J. Read, Susan F. Leitman, Richard Childs, Scott R. Solomon, A. John Barrett, Lineage-specific engraftment and outcomes after T-cell-depleted peripheral blood stem cell transplant with Flu/Cy/TBI conditioning British Journal of Haematology. ,vol. 130, pp. 733- 739 ,(2005) , 10.1111/J.1365-2141.2005.05665.X
C Scheffold, M Kroeger, M Zuehlsdorf, J Tchinda, G Silling, G Bisping, M Stelljes, T Buechner, W E Berdel, J Kienast, Prediction of relapse of acute myeloid leukemia in allogeneic transplant recipients by marrow CD34+ donor cell chimerism analysis. Leukemia. ,vol. 18, pp. 2048- 2050 ,(2004) , 10.1038/SJ.LEU.2403507
Marie Jaksch, Mehmet Uzunel, Mats Remberger, Berit Sundberg, Jonas Mattsson, Molecular monitoring of T-cell chimerism early after allogeneic stem cell transplantation may predict the occurrence of acute GVHD grades II-IV. Clinical Transplantation. ,vol. 19, pp. 346- 349 ,(2005) , 10.1111/J.1399-0012.2005.00345.X
Joseph H Antin, Richard Childs, Alexandra H Filipovich, Sergio Giralt, Stephen Mackinnon, Thomas Spitzer, Daniel Weisdorf, Establishment of complete and mixed donor chimerism after allogeneic lymphohematopoietic transplantation : recommendations from a workshop at the 2001 Tandem Meetings of the International Bone Marrow Transplant Registry and the American Society of Blood and Marrow Transplantation Biology of Blood and Marrow Transplantation. ,vol. 7, pp. 473- 485 ,(2001) , 10.1053/BBMT.2001.V7.PM11669214
Kenneth J. Livak, Thomas D. Schmittgen, ANALYSIS OF RELATIVE GENE EXPRESSION DATA USING REAL-TIME QUANTITATIVE PCR AND THE 2(-DELTA DELTA C(T)) METHOD Methods. ,vol. 25, pp. 402- 408 ,(2001) , 10.1006/METH.2001.1262
Markus Y. Mapara, Megan Sykes, Induction of Mixed vs Full Chimerism to Potentiate GVL Effects After Bone-Marrow Transplantation Adoptive Immunotherapy. ,vol. 109, pp. 469- 474 ,(2005) , 10.1385/1-59259-862-5:469