Differentiating Choroid Plexus Tumors from Metastatic Carcinomas: Use of Inwardly Rectifying K+ Channel KIR7.1 and Excitatory Amino Acid Transporter-1

摘要: The choroid plexus is a villous structure within the ventricular system of brain and consists fibrovascular stroma with fenestrated blood vessels, which covered by epithelium. epithelium neuroectodermal origin bears both features glial epithelial cells. Tumors (CPT) include papilloma (CPP), atypical CPP carcinoma (CPC). are typically papillary tumors that may contain areas solid growth. CPC pleomorphic predominantly Thus, histological distinction CPT be difficult from both, metastasis well differentiated adenocarcinomas less carcinomas. CPTs rare neoplasm’s most frequently affecting children. In contrast, metastases rather frequent but usually arise in adult elderly patients. overall frequency solitary to or its direct vicinity outnumbers primary CPT. differential diagnosis should always considered additional immunostainings required, especially Under this point view, value limits several antibodies summarized significant role Kir7.1 EAAT1 sustained.