Neonatal Candidiasis: New Insights into an Old Problem at a Unique Host-Pathogen Interface

摘要: Candida species are the leading cause of invasive fungal infections in premature infants. Associated with substantial morbidity and mortality, these represent serious sometimes catastrophic complications course hospitalization a preterm infant neonatal intensive care unit. Although virulence factors host defense mechanisms that important protection from candidiasis have been subject study, considerably less is known about features this disease specific to neonates. As animal models for developed, efforts understand similarities differences relative other immunocompromised patients begun provide insights questions.