Biotechnological interventions in Withania somnifera (L.) Dunal

摘要: Withania somnifera is one of the most valued plants and extensively used in Indian, Unani, African systems traditional medicine. It possess a wide array therapeutic properties including anti-arthritic, anti-aging, anti-cancer, anti-inflammatory, immunoregulatory, chemoprotective, cardioprotective, recovery from neurodegenerative disorders. With growing realization benefits associated challenges improvement W. somnifera, studies on exploration genetic chemotypic variations, identification characterization important genes, understanding secondary metabolites production their modulation has gained significant momentum. In recent years, several vitro vivo preclinical have facilitated validation potential phytochemicals derived provided necessary impetus for gaining deeper insight into mechanistic aspects involved mode action these pharmaceutically active constituents. The present review highlights some current developments future prospects biotechnological intervention this medicinal plant.