Use of TGF-β3, to prevent or retard fistula closure following glaucoma filtration surgery

作者: Billie M. York , Jon C. Nixon

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摘要: The intraocular use of TGF-β 3 in connection with glaucoma filtration surgery is described. A composition containing applied to the surgical site suppress production and/or alter extracellular matrix synthesized by fibroblasts at site, and thereby reduce formation scar tissue consequent impairment outflow aqueous humor through a fistula created during surgery.

参考文章(10)
R. Derynck, P. B. Lindquist, A. Lee, D. Wen, J. Tamm, J. L. Graycar, L. Rhee, A. J. Mason, D. A. Miller, R. J. Coffey, A new type of transforming growth factor-beta, TGF-beta 3. The EMBO Journal. ,vol. 7, pp. 3737- 3743 ,(1988) , 10.1002/J.1460-2075.1988.TB03257.X
Ann F. Hanham, Bert M. Glaser, Bruce B. Pharriss, George A. Ksander, METHOD OF TREATING OPHTHALMIC DISORDERS USING TGF-$g(b) ,(1993)
Mamta Shah, Mark William James Ferguson, Wound healing and treatment of fibrotic disorders ,(1993)
Edward P Amento, L Steven Beck, None, Method of predisposing mammals to accelerated tissue repair ,(1991)
MOISE M. TAHERY, DAVID A. LEE, Pharmacologic Control of Wound Healing in Glaucoma Filtration Surgery Journal of Ocular Pharmacology and Therapeutics. ,vol. 5, pp. 155- 179 ,(1989) , 10.1089/JOP.1989.5.155
Ramesh C. Tripathi, Navaneet S. C. Borisuth, Brenda J. Tripathi, Growth factors in the aqueous humor and their therapeutic implications in glaucoma and anterior segment disorders of the human eye Drug Development Research. ,vol. 22, pp. 1- 23 ,(1991) , 10.1002/DDR.430220102
P. ten Dijke, P. Hansen, K. K. Iwata, C. Pieler, J. G. Foulkes, Identification of another member of the transforming growth factor type beta gene family Proceedings of the National Academy of Sciences of the United States of America. ,vol. 85, pp. 4715- 4719 ,(1988) , 10.1073/PNAS.85.13.4715
Roberts Ab, Sporn Mb, Transforming growth factor beta. Advances in Cancer Research. ,vol. 51, pp. 107- ,(1988)