Determination of arsenic compounds by high-performance liquid chromatography-ultrasonic nebulizer-high power nitrogen-microwave-induced plasma mass spectrometry: an accepted coupling.

摘要: To establish a sensitive, accurate, and precise determination of arsenic compounds, high power nitrogen microwave-induced plasma (1.3 kW) mass spectrometer (N2-MIP-MS) has been successfully coupled with an ultrasonic nebulizer (HPLC-USN) that is attached to high-performance liquid chromatograph. It examined as element-specific detector for its applicability the optimization seven compounds [arsenic acid, methylarsonic acid (MA), dimethylarsinic (DMA), arsenobetaine (AB), arsenocholine (AC), trimethylarsine oxide (TMAO), tetramethylarsonium ion (TMI)]. This HPLC-USN-MIP-MS coupling encouraging combination alternative method spectroscopy elemental speciation analysis. Interchanging MIP-MS fabricated (concentric) nebulizer, increases 3−6 times signals anionic 6−12 those cationic compared traditional methods. The u...