Intraoperative angiography with indocyanine green to assess anastomosis perfusion in patients undergoing laparoscopic colorectal resection: results of a multicenter randomized controlled trial.

摘要: Insufficient vascular supply is one of the main causes anastomotic leak in colorectal surgery. Intraoperative indocyanine-green (ICG) angiography has been shown to provide information on tissue perfusion, identifying a well-perfused location for colonic and rectal transections, thus possibly reducing rate. Aim this study was evaluate usefulness intraoperative assessment perfusion using ICG patients undergoing left-sided colon or resection with anastomosis. This randomized trial involved 252 laparoscopic 1:1 subjective visual evaluation bowel without ICG. The primary aim assess whether could lead reduction Secondary outcomes were possible changes surgical strategy postoperative morbidity. After randomization, 12 excluded. Accordingly, 240 included analysis; 118 group, 122 control group. showed insufficient colic stump, which led extended 13 cases (11%). An developed 11 (9%) group 6 (5%) (p = n.s.). fluorescent can effectively vascularization stump anastomosis resection. method further proximal cases, however, there no statistically significant rate arm. ClinicalTrials.gov NCT02662946.