A Catalytic Enantioselective Aza‐Michael Reaction: Novel Protocols for Asymmetric Synthesis of β‐Amino Carbonyl Compounds
作者： Li-Wen Xu , Chun-Gu Xia
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摘要: β-Amino carbonyl functionalities are ubiquitous motifs in natural and nonnatural products such as alkaloids poly-ketides. Among the reactions for synthesis of β-amino car-bonyl compounds β-substituted acids, aza-Michael using catalytic amounts chiral Lewisacids might provide best methods generation optically active compounds. During last five years, asymmetric reaction has emerged a very powerful tool compounds, will be discussed this microreview. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
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