Validity of the captopril test for identifying correctable unilateral renovascular hypertension.

摘要: In order to validate the captopril test for identification of patients with renovascular hypertension (RVH), we performed 118 suspected suffering from RVH who were receiving antihypertensive medication. On basis 44 proven and 74 primary (PH), sensitivity, specificity posterior probability calculated separately undergoing not diuretic therapy. An absolute rise in plasma renin activity (PRA) a relative PRA served as discriminating indicators. The increase after administration absence long-term therapy diuretics yielded best one-dimensional model, sensitivity 89% 97%. Linking variables "absolute" "relative PRA" reduced misclassification rate 5%. This validation allows an accurate distinction between PH on even when is suspended (except ACE inhibitors diuretics).