作者: Neal L. Benowttz , Sharon M. Hall , Ronald I. Herning , Peyton Jacob , Reese T. Jones
DOI: 10.1056/NEJM198307213090303
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摘要: Abstract Advertisements suggest that smokers of cigarettes low in nicotine are exposed to less and tar. Nicotine yields measured with smoking machines, but machines do not smoke as people do. We therefore the actual content commercial different tar determined also intake indicated by blood concentrations its metabolite, cotinine, 272 subjects various brands cigarettes. found low-yield cigarette tobacco did contain nicotine; fact, concentration inversely correlated (r = -0.53, P<0.05) machines. Blood cotinine number smoked per day yield Only 3.8 5.0 cent total variance was contributed yield. conclude low-ni...